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Bashir Ahmad Sanaie

Bashir Ahmad Sanaie

Govt. Medical College Srinagar, India

Title: Transverse myelitis caused by varicella zoster virus in an immunocompetent patient – A case report

Biography

Biography: Bashir Ahmad Sanaie

Abstract

Varicella zoster virus infection causes chicken pox and herpes zoster. Varicella zoster virus can be latent in cranial nerve or dorsal root ganglia. Reactivation after several years/decades later produce rash and post herpetic neuralgia and severe neurological complications like cranial nerve palsies, zoster paresis, meningoencephalitis, cerebellitis, leukoencephalopathy, myelopathy, poly radiculoneuritis, ganglionitis, progressive outer retinal necrosis, stroke, necrotizing angitis etc. Herpes zoster myelitis usually occurs in immunocompromised and elderly patients and is very uncommon in immunocompetent patients. We report here a case of herpes zoster myelitis involving cervical and dorsal cord in an immunocompetent patient. A 55 years
old lady admitted in our department with insignificant past medical history with complaints of papulovesicular rash and pain along D4 and D5 distribution. Twelve days later, it was followed by pain, paresthesias, weakness left lower limb and bladder involvement. MRI showed evidence of myelitis in C6 to D11 region. Serum and CSF showed high levels of anti-varicella zoster
IgG levels. We treated patient with acyclovir for two weeks and methylprednisolone (1g) daily for three doses. Patient showed significant sensory, bladder and motor function improvement after two weeks. One month after treatment patient became steady and ambulatory. We suggest consideration of zoster myelitis in immunocompetent patient and early treatment with anti-virals and steroids.