26^th European Neurology Congress

Autism spectrum disorders (ASD) are common heterogeneous neurodevelopmental disorders, characterized by disruptions in social interactions, communication and limitations in behaviour. Early diagnosis is an important step to prevent progression of ASD. Recent developments in genetic technology provide useful tools to investigate molecular mechanisms involved in autism. Despite a number of noteworthy studies, there is not yet enough understanding of the genetic aetiology of ASD. Research should focus on multidisciplinary approaches to improve early diagnosis and intervention of autism. It is important to study combinatorial effects of genetic, epigenetic, environmental factors. Current research in ASD highlights the importance of identifying new approaches such as next generation sequencing (NGS) and microRNA (miRNA) technologies to develop new biomarkers and drugs. Our study focus on identify common gene variation in ASD patients and also novel

genes for early diagnosis using NGS.