Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 32nd world congress on Neurology and Therapeutics Barcelona, Spain.

Day 1 :

Keynote Forum

Huang Wei Ling

Medical Acupuncture and Pain Management Clinic, Brazil

Keynote: What is behind a brain tumor that we need to know to avoid surgery?
Conference Series Neurology 2023 International Conference Keynote Speaker Huang Wei Ling photo
Biography:

Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she works with the approach and treatment of all chronic diseases in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates. Researcher in the University of São Paulo, in the Ophthalmology department from 2012 to 2013.Author of the theory Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine.

 

Abstract:

Introduction: The most prevalent brain tumors are metastasis of systemic cancers, meningioma’s, gliomas, and glioblastomas. The purpose of this study is to demonstrate that all patients with cancer have in the background an energy deficiency inside the five internal massive organs (Liver, Heart, Spleen, Lungs, and Kidney) of the Five Elements theory of traditional Chinese medicine and the treatment of this condition can reduce the size of the tumor or can cure the patient.

Methods: one case report of 45 years-old male patients, he is the son of my patient in Brazil, but he lives in London. My patient said that she needs to go to London because her son has a brain tumor and I told her to take the medications that she was using for him (highly diluted medications according to the theory Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine).

Results: after about two months, the patient’s mother called me and said that he does not need to do the surgery because his symptoms improved and the size of the tumor reduced after using the medications. The conclusion of this study is to demonstrate that patients with a brain tumor have energy deficiency inside the five internal massive organs as the cause of brain tumor formation and the treatment of replenishing these energies using highly diluted medications will reduce the tumor size without using surgery.

 

  • Neurology Insights and Innovations | CNS and Brain disorders | Neurodegenerative Disorders | Clinical Neurology and Neurosurgery | Neuroinfections and Neuroimmunology | Cognitive Neuroscience | Neurological Disorders | Neurotherapeutics | Neuropathology | Neurocognitive Disorder | Neurooncology | Cognitive Control | Common Neurological and Psychiatric Diseases | Cognitive and Behavioral Neuroscience
Location: Webinar
Biography:

Mohamed H. Yousef currently working in the School of Sciences and Engineering, Biotechnology Graduate Program, The American University in Cairo, Cairo, Egypt.

Abstract:

Glycogen Synthase Kinase 3 (GSK3) is associated with the proinflammatory phenotype of microglia and has been shown to act in concert with nuclear factor kappa B (NF-κB). GSK3 is also a suppressor of nuclear factor erythroid 2-related factor 2 (Nrf2), the principal regulator of redox homeostasis. Agreeing with the oxidative paradigm of aging, Nrf2 is often deregulated in parainflammatory and neurodegenerative diseases. In this study, we aimed to explore a multimodal disease-modifying utility of GSK3 inhibition, beyond neuronal proteopathologies, Furthermore, we aimed to underscore the difference in therapeutic value between the two GSK3 paralogs by isoform-selective chemical inhibition.
 
The anti-inflammatory effects of paralog-selective GSK3 inhibitors were evaluated as a function of the reductive capacity of each to mitigate LPS-induced activation of SIM-A9 microglia. The Griess method was employed to detect the nitrate-lowering capacity of selective GSK3 inhibition. Real-time PCR was used to assess post-treatment expression levels of pro-inflammatory markers and antioxidant genes; pro-inflammatory cytokines were assayed by ELISA. Nuclear lysates of treated cells were examined for Nrf2 and NF-κB accumulation by immunoblotting. Finally, to infer whether the counter-inflammatory activity of GSK3 inhibition was Nrf2-dependent, DsiRNA-mediated knockdown of Nrf2 was attempted.
 
Results from our experiments reveal a superior anti-inflammatory and anti-oxidative efficacy for GSK3β-selective inhibition, compared to GSK3α-selective and non-selective pan-inhibition; hence use of selective GSK3β inhibitors is likely to be more propitious than non-selective dual inhibitors administered at comparable doses. Moreover, our results suggest that the anti-inflammatory effects of GSK3 inhibition is not Nrf2 dependent.

Isha Akulwar-Tajane

K. J. Somaiya College of Physiotherapy, India

Title: Functional neurological disorder: A scoping review
Speaker
Biography:

Isha Akulwar-Tajane experienced Associate Professor with a demonstrated history of working in academic institute, hospital & health care industry. Skilled in research and statistics, clinical research, clinical trials, and Good Clinical Practice (GCP). Strong sales professional with a M.P.Th. focused in Neurosciences Physiotherapy from Maharashtra University of Health Sciences.

 

Abstract:

Aim & Objectives: To summarize the available evidence so far and bring forth crucial queries for general neurologists and specialists dealing with functional neurological disorder (FND) patients; address medical and rehabilitation services; and highlight the research areas regarding management of FND.

Hypothesis: NA

Materials and Methods: A scoping review conducted according to PRISMAScR guidelines. Electronic database was searched using the MeSH terms -functional neurologic disorder, hysteria, conversion disorder, psychogenic or non-organic illness.

Result: Studies were subjected to ‘narrative review’ of the process-oriented data and simple quantitative analysis using descriptive statistics. Key themes were centered around– clinical and functional significance; challenges in diagnosis; treatment effectiveness; role of Physiotherapy, etc.

Conclusion: Functional neurological disorders is a common cause of persistent and disabling neurological symptoms; has poor psychosocial outcomes; and is a neglected source of disability. Encouraging studies support the potential reversibility of FND with specifically tailored treatments. Promising evidence has accumulated for the benefits of specific physical rehabilitation and psychological interventions alone or in combination, but clinical trial evidence remains limited. Further research is warranted to determine the dose and duration of various interventions; the value of combination treatments & multidisciplinary therapy; and the therapeutic modality best suited for each patient.

 

 

Birendra Kumar Pankaj

JMD Brain & Nerve Clinic, India

Title: Approach to a case of vertigo

Time : 14:00-14:30

Speaker
Biography:

Birendra Kumar Pankaj MD (General Medicine), DM (Neurology), CAC Neurology (Queens Square, London) is a Senior Consultant Neurophysian and Director of JMD BRAIN AND NERVE CLINIC, Jharkhand, India for last 21 years. He has organized many neurological conferences .He has attended more than 100 national and international neurological conferences as delegate, chairperson and speaker. He is currently vice president of Jharkhand state IMA. He is life member of many national and international neurological associations and societies. He was organizing secretary of ANEIMIDCON 2012 and many national conferences. He has few publications also. He has organized more than 100 neurological free checkup and free drug distribution in rural and underprivileged population. He has conducted many webinars and awareness programmers for benefit of society. His key interests are Headache, Epilepsy, Electrophysiology, Vertigo and Stroke.

 

Abstract:

Vertigo is a relevant clinical symptom and patients with vertigo have more distress and disability. Vertigo has been classified as peripheral and central according to site of lesion and also depending on the duration. There are many clinical examination and tests to differentiate central and peripheral vertigo.

Cardiovascular examination, head, neck and ear examination and bedside examination of the vestibular and ocular motor systems are essential for diagnosis of vertigo and their management. Head impulse test, Rhombergs test, Dix hall pipe maneuver, Head tilt test, Supine roll test, Hearing test and ocular tilt reaction are some of important bed side tests. Eng and Vng are some important laboratory tests.

Vestibular paroxysmia, benign postural vertigo, perilymph tic fistula and phobic postural vertigo are some important short duration differentials. Mennier's disease, Vestibular migraine, Tia and episodic ataxia type 2 are some of long duration differentials.

Vertbrobasilar stroke, vestibular neuritis, bilateral vestibulopathy, degenerative disease (cerebellar ataxia), multifactorial vertigo in the elderly, somatoform/ phobic vertigo are some more prolonged duration differentials. Treatment of vertigo varies according to the cause and vestibular rehabilitation is one of the important aspects of management along with ant vertigo drugs. Dose and duration of anti-vertigo medication varies according to cause of vertigo. Surgery is also required in few diseases causing vertigo when conservative therapy fails.

Speaker
Biography:

Brandon Lucke-Wold was born and raised in Colorado Springs, CO. He graduated magna cum laude with a BS in Neuroscience and distinction in honors from Baylor University. He completed his MD/PhD, Master’s in Clinical and Translational Research, and the Global Health Track at West Virginia University School of Medicine. His research focus was on traumatic brain injury, neurosurgical simulation, and stroke. At West Virginia University, he also served as a health coach for the Diabetes Prevention and Management program in Morgantown and Charleston, WV, which significantly improved health outcomes for participants. In addition to his research and public health projects, he is a co-founder of the biotechnology company Wright-Wold Scientific, the pharmaceutical company CTE cure, and was a science advocate on Capitol Hill through the Washington Fellow’s program.

 

Abstract:

Neonatal hydrocephalus is a neurologic congenital condition where excess CSF accumulates in the brain’s ventricles and aqueducts, causing increased intracranial pressure. Global rising rates of neonatal hydrocephalus call for a better understanding of the etiology and advancement of more modernized therapeutic approaches. Currently, causes of neonatal hydrocephalus are believed to be genetic or from acquired injuries. Socioeconomic factors and maternal comorbidities also affect the health outcomes of neonatal hydrocephalus patients. Evaluation of development, presence, and recovery from neonatal hydrocephalus are through brain imaging, physical examination, and history taking. Infants with the condition most experience little loss of neurological function, but a significant fraction also faces worsening morbidities and sudden fatality. The two major treatments for the condition are ventriculo-subgaleal shunt (VSGS) and endoscopic third ventriculostomy (ETV), and both carry high risks of perioperative complications. Nevertheless, the chosen therapy for each patient requires consideration of their health status, and more importantly, their informed decision. The patient should also be informed about postoperative management and the importance of regular follow-ups with their neurosurgeon and neurologist.