Frank C Barone
Professor and Director
SUNY Downstate Medical Center
USA
Biography
Accomplished leader with significant experience as researcher, professor and consultant in Drug Discovery and Academia. Significant contributions to discovering drugs, to increasing the understanding of drug action and to the biology of several diseases. Strong scientific, management and communication skills demonstrated in all endeavors. Established track record of building functional, cohesive research teams that are empowered to meet and exceed research goals. Specifics include: --25 years in Drug Discovery functioning as research team leader in developing and executing research strategies from target discovery to drug screening and target validation in disease to marketed drug and post-market drug scientific support; History of maintained/consistent research/resource support in industrial environment for disease target research and compound progression in Discovery Research. --Significant experience as consultant to Pharmaceutical Companies, and in the academic work environment helping to developing research direction, helping to secure federal research grant support and teaching. --Ability to Integrate Systems Pharmacology/Biology and Translational Medicine into Drug Discovery and Disease Biology Research. --Long standing research background/experience in cardiovascular and cerebrovascular diseases. --Member of journal editorial boards and NIH study groups; scientific reviewer to many journals, granting organizations and study groups/sections; member of numerous scientific societies; four faculty appointments; currently have published over 200 scientific manuscripts, reviews, chapters and patents.
Research Interest
Basic scientific study of Cerebrovascular diseases with focus on stroke, vascular cognitive impairment, risk factors, brain injury and restoration of function, and progression to dementia Development of animal models of human disease that can translate well to man and can facilitate our understanding of disease biology, pathology and cellular signaling Investigation of pharmacologic and other intervention approaches that reduce brain injury and restore lost brain functioning Pursue Biomarker Discovery required to impact drug discovery and advance therapeutic interventions Maintain close collaborations with Clinical Researchers and Neuroscientists in efforts to support Translational Medicine