15^th European Neurology Congress August 29-31, 2017 London, UK

Biography:

Wai Kwong Tang was appointed to professor in the Department of Psychiatry, the Chinese University of Hong Kong in 2011. His main research areas are Addictions and Neuropsychiatry in Stroke. Professor Tang has published over 100 papers in renowned journals, and has also contributed to the peer review of 40 journals. He has secured over 20 major competitive research grants, including Health and Medical Research Fund, reference number: 02130726. Health and Medical Research Fund, reference number: 01120376. National Natural Science Foundation of China, reference number: 81371460. General Research Fund, reference number: 474513. General Research Fund, reference number: 473712. He has served the editorial boards of five scientific journals. He was also a recipient of the Young Researcher Award in 2007, awarded by the Chinese University of Hong Kong. 

Abstract:

Depression is common following an acute stroke. Poststroke Depression (PSD) have notable impacts on the function recovery and quality of life of stroke survivors. Incidence decreased across time after stroke, but prevalence of PSD tend to be stable. Many studies have explored the association between lesion location and the incidence of PSD. For example, lesions in frontal lobe, basal ganglia and deep white matter have been related with PSD. Furthermore, cerebral microbleeds and functional changes in brain networks have also been implicated in the development of PSD. In this presentation, evidences of such association between the above structural and functional brain changes and PSD will be reviewed.

Acknowledgement:

This project is supported by the following grants.

1.         Health and Medical Research Fund, reference number: 02130726

2.         Health and Medical Research Fund, reference number: 01120376

3.         National Natural Science Foundation of China, reference number: 81371460

4.         General Research Fund, reference number: 474513

5.         General Research Fund, reference number: 473712

Biography:

Giovanni Antioco Putzu is a Medical Doctor since 1992, with specialization in Paediatric Neurology. He achived his PhD in 1996. During PHD studies, He was a Research Fellow in Hammersmith Hospital of London, UK in 1992, then He moved in Marseille to work at INSERM (Genetics) and in Neurophathology. The Author has published more than 15 papers in the field of Neuromuscular Disorders.

Abstract:

Biography:

Xi Huang completed his PhD from Fourth Military Medical University(FMMU) in 1995 and Postdoctoral studies from Xiyuan Hospital, China Academy of Chinese Medicine Science in 1998 respectively. He is the Director and Professor of Institute of TCM-related depressive comorbidity, Nanjing University of Chinese Medicine (NUCM). He is respectively a Lead Clinician in Xijing Hospital of FMMU, West China Hospital of Sichuan University and Xiangya Hospital of Central South University of China. He has got 9 funds from o National Natural Science Foundations of China. He is the corresponding author of more than 200 papers out of which 41 is of Traditional Chinese Medicine published in SCI journals. He is the Editorial Board Members or Correspondence Reviewer of more than 10 reputed journals. He is also the Chairman of Basic Theory Committee of China Association of Integrated Medicine.

Abstract:

Functional dyspepsia or coronary heart disease and depression(F/C&D) often coexist with high incidence, suggesting unique challenge for human life and available tailored theories from one disease. One of most challenge is weak unified theory without explaining comorbidity of F/C&D (CF/C&D), including: i)molecules in separately and alone mediating mood/brain or circulation/cardiovascular system or digestion/gut in different studies; ii)above molecules without pharmacodynamic integration by one compound-induced simultaneous antidepressants and prokinetic(A&P) pharmacology; iii)Negligence of Gan (≈CF/C&D’s biology) and Shu-Gan (≈CF/ C&D’s therapy and pharmacology) whose actual A&P efficacy have acted for 2200 years. Our previous viewpoints or ideas from abstracts for us attending other conferences only involved in gut and brain or their signal, A&P actions and its integrated shared molecules in regulating gut-brain disorder after stress. The present goal is to elucidate shared biology in gut/heart-brain interaction following stress via providing commonalities in signal molecules, pathway and pharmacology integrated by Gan and Shu-Gan. Results from literature and our recently unpublished researches include: a. No shared biology or unified theory about gut/heart-brain interaction following stress and CF/C&D are available from literature. Gan and Shu-Gan are ancient unified theory or shared biology for simultaneously regulating mood, digestion and circulation in pathophysiology and pharmacology, without widely accepted scientific explanation and strictly designed scientific documents for this theory; b. Brain (hippocampus, CA3 region and neuron et. al.), gut (intestinal epithelium, miR-222, gut microbiome, serotonergic system, tryptophan metabolism, brain-gut-microbiome axis) and cardiovascular system (vulnerable atherosclerotic plaque and chondriosome) are vulnerable to stress; c. High incidences are respectively depressive comorbidity with Functional gastrointestinal disorder (FGIDs) (93%) and coronary heart disease (15~45%); d. one TCM (Traditional Chinese Medicine) is respectively effective; e. We find simultaneous activities against CF/C&D by ferulic acid and meranzin hydrate. Their shared mechanism involved in stress and ghrelin regulation are in progress. Such shared signal molecules and pharmacological compounds will highlight CF/C&D researches.

Biography:

Pankaj Sharma is a Consultant Neurologist at Imperial College London and Professor of Neurology at the Royal Holloway University of London where he is also Director of the Institute of Cardiovascular Research. He was a former Dept of Health Senior Fellow,head of acute stroke services at Hammersmith Hospitals and headof the Imperial College Cerebrovascular Research Unit. He currently is Honorary Medical Director of the UK national charity Different Stroke and Editor-in-Chief of the Royal Society of Medicine Cardiovascular Disease journal. He is a fellow of the Royal College of Physicians (as well as an examiner) and the Medical Society of London, and a member of the Association of British Neurologist and the British Hypertension Society. He trained in general medicine, clinical pharmacology and neurology and is the only UK neurologist to hold specialist European accreditation in the management of hypertension. He holds doctorates from the universities of London and Cambridge. He was a former British Heart Foundation Clinician Scientist at Cambridge and a Fulbright Scholar at Harvard Medical School & Massachusetts General Hospital, USA. His research interests include the genetics of stroke (including in ethnic minority populations).

Abstract: