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Nathali Kaushansky


Nathali Kaushansky

The Weizmann Institute of Science, Isreal

Biography

Nathali Kaushansky, PhD, is a staff scientist in the Neurobiology Department at the Weizmann institute of Science. Dr. Kaushansky received her BSc in Chemistry and MSc in Biomedical Engineering from the Technion – Israel Institute of Technology, Haifa, Israel. She completed her PhD studies and post-doctoral training in the Immunology Department in The Weizmann Institute of Science. In the last 10 years Dr. Kaushansky’s work has focused on characterization of autoimmune T- and B-cells against myelin and neuronal target antigens in Multiple Sclerosis (MS). Her study aims to establish a highly specific “multi – targeting” immunomodulatory approach via co-antagonizing of most known and potentially pathogenic T-cell autoreactivities in MS. The primary goals of her recent research were 1: studying mechanisms underlying immunomodulation by this multi epitope targeting agent (specifically designed artificial multi-epitope protein (Y-MSPc)-recently published) and 2: studying immunogenetics of susceptibility to MS, mainly at defining HLA-DR2-related epitopes of the different most important myelin target antigens in MS.

Abstract

Abstract : Modulation of MS-like disease by regulatory CD11c+CD11b+Gr1+ Myeloid-derived Dendritic cells induced by Antigen-specific therapy with synthetic multi epitope protein