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Marco Carotenuto

Marco Carotenuto

Università degli Studi della Campania “Luigi Vanvitelli”, Italy

Title: Cyclic Alternating Pattern (CAP) analysis in children affected by migraine without aura: a preliminary study

Biography

Biography: Marco Carotenuto

Abstract

Introduction: Children with migraine headaches appear to have a range of sleep disturbances. The aim of the present study is to assess the NREM sleep instability in a population of school-aged individuals affected by migraine without aura MoA.

Materials and Methods: 33 children with MoA (20 males, 13 females, mean age 10.45 years, SD 2.06) underwent overnight PSG recordings and the Cyclic alternating pattern (CAP) was performed, according with international criteria.

Results: MoA group shows significant reduction in sleep duration parameters (TIB, SPT, TST; p≤0.001 for all) and a significant increase in awakenings per hours (AWK/h) (p=0.008) About the NREM sleep instability analysis findings, the MoA children show a reducted CAP rate% (p≤0.001), CAP rate% in S1 (p≤0.001) and in CAP rate% in SWS (p=0.004). Moreover, the A phases distribution were characterized by significant reduction in slow wave components (Total number CAP A1%, CAP A1 index) (p≤0.001) and an increasing in fast components (Total number of CAP A2% and CAP A3%) representation. MoA children show also an increased A1 and A2 mean duration (p≤0.001)

Conclusion: Poor sleep quality and NREM sleep instability are associated with MoA in children.